Deciphering the Role of the Placenta in Abnormal Pregnancies

Our aim is to...

Provide tools for scientists and clinicians to better identify women and babies at risk for abnormal pregnancy outcomes.

Develop new intervention strategies for patients who suffer from 'poor placentation' to prevent the development of diseases, such as the hypertensive disorder preeclampsia and intra uterine growth restriction.

Close the gap between detection and treatment of high risk pregnancies by combining fundamental placental biology research, with new cutting edge technologies that is highly disruptive and clinically relevant.


These are amazing times in reproductive biology. Our research is moving forward to help women and babies at risk as early as five weeks of pregnancy
— Dr Randall Armant, Wayne State University, School of Medicine

Center of Advanced Trophoblast Research

The Center of Advanced Trophoblast Research, aims to close the gap between the diagnosis and treatment of placental dysfunction. Our research uses a distinctive approach as it combines two innovative methodologies:

  1. Develop a risk assessment methodology to determine the best treatment for patients.
  2. Generate the means to treat the organ that holds the key to successful pregnancy (i.e., the placenta).

This is truly an exciting time for reproductive biology and medicine. This innovative research will provide new, critical insights into early human development and mechanisms of disease. The insights will inform the development of safe and reliable tests to identify women at risk for obstetric complications during pregnancy and help better manage diseases appropriately. We are building upon this unique strength to achieve our ultimate collaborative goal of personalized medicine for every pregnant woman and baby.


Make sure to check out the great resources and support the Preeclampsia Foundation and March of Dimes Foundation offer.